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  1. MTHFR Gene Variant and Folic Acid Facts | Folic Acid | CDC

    May 27, 2025 · You may have heard that if you have an MTHFR variant, you should avoid folic acid and should take other types of folate, such as 5-MTHF. However, this is not true.

  2. MTHFR Gene Mutations: What You Need to Know - WebMD

    MTHFR gene mutation affects folate metabolism, linked to higher risk of cardiovascular issues, blood clots, and certain birth defects. It influences methylation and homocysteine levels.

  3. MTHFR mutation: Symptoms, testing, and treatment

    Aug 21, 2025 · Methylenetetrahydrofolate reductase (MTHFR) is an enzyme that breaks down the amino acid homocysteine. If the MTHFR gene that codes for this enzyme mutates, it may contribute to …

  4. MTHFR Gene Mutation: Symptoms, Testing, and Treatments

    Feb 25, 2025 · MTHFR is a gene everyone has. Some mutations of the MTHFR gene may be associated with health problems and complications in pregnancy. Learn about determining your …

  5. Methylenetetrahydrofolate reductase - Wikipedia

    Methylenetetrahydrofolate reductase catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a cosubstrate for homocysteine remethylation to methionine. Natural …

  6. MTHFR is a gene that makes an enzyme called MethyleneTetraHydroFolate Reductase. This enzyme works with a B-vitamin called folate. Together, MTHFR and folate help to reduce the level of …

  7. MTHFR Gene: Key Facts, Symptoms, and Treatment Options

    The MTHFR gene is essential for processing folate in the body. Mutations in this gene can lead to elevated homocysteine levels, which are linked to various health issues, including cardiovascular …

  8. The MTHFR Panic Is Over: What Actually Drives Detox Problems Today

    Dec 3, 2025 · The MTHFR Mutation Is Overhyped – Here’s What Actually Matters for Methylation and Detox in 2025 For nearly a decade, the MTHFR gene has been a centerpiece of online health …

  9. MTHFR gene: MedlinePlus Genetics

    The MTHFR gene provides instructions for making an enzyme called methylenetetrahydrofolate reductase. Learn about this gene and related health conditions.

  10. MTHFR Gene Mutations Explained: Symptoms, Risks & Testing Guide

    Jun 2, 2025 · Everything on MTHFR gene mutations, impact on health, symptoms, and testing. How MTHFR affects methylation, folate, and homocysteine—plus natural ways to manage it.