In a recent article published in the journal Nature, researchers used a classical concept in computational linguistics to design a new algorithm, LinearDesign, which optimized the structural stability ...

How does the cell convert DNA into working proteins? The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But ...

Baidu Inc.’s preclinical studies showed the mRNA vaccine sequences for COVID-19 designed using its Lineardesign algorithm outperformed the benchmark sequences designed by traditional algorithms in ...

Daniel E. Eyler, Monika K. Franco, Zahra Batool, Monica Z. Wu, Michelle L. Dubuke, Malgorzata Dobosz-Bartoszek, Joshua D. Jones, Yury S. Polikanov, Bijoyita Roy, Kristin S. Koutmo Proceedings of the ...

In the fast-evolving field of medical science, a new artificial intelligence model may be about to change the way mRNA-based drugs and vaccines are designed. Developed through a collaboration between ...

Transcription and translation are processes a cell uses to make all proteins the body needs to function from information stored in the sequence of bases in DNA. The four bases (C, A, T/U, and G in the ...

The manufacture and release of mRNA therapeutics and vaccines is a complex and challenging process requiring a high degree of expertise, capabilities, and experience. The development and manufacturing ...

As soon as mRNA vaccines demonstrated startling efficacy against SARS-CoV-2 and began rolling out late last year, the virus revealed its slippery nature. The mRNA vaccines now in use are based on ...

A new technique reveals ribosome cooperativity, providing new insights into protein production. Researchers from Marvin Tanenbaum’s group at the Hubrecht Institute (Utrecht, Netherlands) have ...