Assembly and budding of a virus from a membrane microdomain. Viruses have an outer protein shell called a capsid which surrounds the viral nucleic acid. Enveloped viruses, such as HIV, have an ...

Though treatments are available, there is no cure or vaccine from HIV, which impacts about 38 million people worldwide. It's difficult to target the RNA genome of the HIV virus in part because it ...

Many pathogenic viruses require a specific structure to be infectious, and their proteins form that structure in vivo with remarkable fidelity. The dynamical process by which protein conformations are ...

A group of University of Chicago scientists announced a groundbreaking study that explores the role of a small molecule, called IP6, in building the HIV-1 virus capsid. The genetic information of the ...

Key PointsResearch on HIV's conical capsid that began over 25 years ago led to the development of lenacapavir, the world's ...

Researchers at the University of Delaware, using supercomputing resources and collaborating with scientists at Indiana University, have gained new understanding of the virus that causes hepatitis B ...

A person doesn't have to get sick to catch a virus. Researchers hope to catch viruses for detection and vaccinations by understanding their sticky outer layers. The complex structures making the ...

In a recent study published in The Lancet Microbe journal, researchers described the effectiveness of a modular capsid virus-like coronavirus disease 2019 (COVID-19) vaccination. Study: First-in-human ...

Some of the most expensive drugs currently in use are gene therapies to treat specific diseases, and their high cost limits their availability for those who need them. Part of the reason for the cost ...