—Do secondary mutations explain why patients with AML with a history of myelodysplasia-related changes and the NPM1 mutation have outcomes that are inferior to those in patients with normal ...
Over the course of treatment, patients with relapsed/refractory acute myeloid leukemia (AML) may acquire new TP53 mutations, making ongoing monitoring for mutations crucial. “New novel therapies ...
Multi-hit TP53 mutations are linked to poor survival in both MPN and AML, with median OS ranging from 4.8 to 11.6 months. Factors such as ASCT, pre-transplant therapy response, and concurrent TET2 or ...
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Acute Myeloid Leukemia Is One of the Most Common Types of Leukemia Among Adults—Look for These Signs
Acute myeloid leukemia (AML) is a type of leukemia, a cancer of the blood and bone marrow. AML specifically affects the myeloid cells, which are immature white blood cells. It is one of the most ...
The illustration of protein structure (domains) on the left side, and corresponding exons in the FLT3 gene are displayed on the right side. FMS-like tyrosine kinase 3 (FLT3) mutations represent some ...
Acute monocytic leukemia (AML-M5) is a subtype of AML, in which at least 80 percent of the affected blood cells are a type of white blood cell called monocytes. Half of the people diagnosed with AML ...
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