Figure 1: Overall structure of the GCGR–NNC0640–mAb1 complex. Figure 2: Ligand-binding mode of GCGR to NNC0640. Figure 3: Stalk and ECL1 in the full-length GCGR structure. The importance of the ...

Class B G-protein-coupled receptors are major targets for the treatment of chronic diseases, such as osteoporosis, diabetes and obesity. Here we report the structure of a full-length class B receptor, ...

Lipid kinases are among the promising targets of new classes of drugs, due mainly to class I PI3Kα, which plays a crucial role in carcinogenesis and metastasis. This enzyme is hyperactive in 30-40% of ...

How can CU Professors/Administration keep students motivated to engage with the material at a level needed to be awarded credit for a college level course while still offering the flexibility and ...

Punjab School Education Board (PSEB) has recently released exam structure for question papers for all subjects. The board has ...

Storskogen Group AB Class B ( ($SE:STOR.B) ) has provided an update. Storskogen Group AB has updated its share and vote structure, reporting a ...

Ford Motor Company has a dual-class stock structure of Class A and Class B shares. The roughly three billion Class A shares are for the general public like you and me, while the roughly 71 million ...