A nucleoside-modified mRNA (modRNA) influenza vaccine showed greater protection against influenza-like illness compared to a standard inactivated vaccine in adults. 2. The modRNA vaccine triggered ...

Modified nucleosides within RNA are involved in maintaining and regulating the protein synthesis system. Archaeosine is a modified nucleoside found only in the tRNAs from archaea, the so-called third ...

This is a preview. Log in through your library . Abstract Combined vaccine formulations targeting not only hemagglutinin but also other influenza virus antigens could form the basis for a universal ...

Researchers found that the relative efficacy of the modRNA vaccine was 34.5% against influenza-like illness compared with the control vaccine, on the basis of 57 and 87 cases in the modRNA and control ...

It’s early October—the time of year when a few, select, researchers receive an early morning phone call from Stockholm. The first of the Nobel prizes awarded, announced on Monday morning, was the ...

Discoveries that enabled mRNA vaccines against COVID-19 have landed two scientists a Nobel Prize. The Nobel Assembly awarded Katalin Karikó, Ph.D., and Drew Weissman, M.D., Ph.D., the prize for their ...

Inosine is a nucleoside that occurs naturally in transfer RNAs (tRNAs) and is essential for proper RNA translation. It is commonly found at the wobble position of anticodons, allowing for greater ...

Katalin Karikó, PhD, is professor at University of Szeged, Hungary, and adjunct professor of neurosurgery at the Perelman School of Medicine, University of Pennsylvania, where she worked for 24 years.