The lymphocyte micronucleus assay was used to measure the average frequency of micronuclei in a population and thus assess genotoxic effects. Data from 174 persons glve an average value of 16.4 ± 7.3, ...
Radiation Research, Vol. 180, No. 3 (September 2013), pp. 284-291 (8 pages) The frequency of binucleated cells containing one or more micronuclei (MNBN cells) in cytokinesis-blocked peripheral blood ...
The cytokinesis-block micronucleus test (MNT), as a marker of chromosomal mutagen sensitivity, was applied in a number of studies enrolling breast cancer (BC) patients and subjects with known or ...
Increased micronucleus frequency in peripheral blood lymphocytes predicts the risk of bladder cancer
Bladder cancer (BC) is among the most common malignancies worldwide. The identification of new biomarkers for early BC detection, recurrence/progression is urgently needed. The cytokinesis-block ...
The induction of micronuclei is a key characteristic of genotoxic compounds; for example, clastrogens produce DNA strand breakage while aneugens interfere with chromosome segregation. As a result, ...
The list of potentially hazardous structural fragments was compiled from various literature sources and refined by analyzing their performance on data from different assays detecting point mutational ...
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