Drug-induced liver injury (DILI) is a harmful reaction to medications, herbs, and dietary supplements that results in liver dysfunction. Based on the distinct clinical patterns of liver damage, DILI ...

Chronic cholestasis, defined as the impairment of bile acid formation and/or flow persisting for more than six months, encompasses a broad spectrum of hepatobiliary disorders, both heritable and ...

Please provide your email address to receive an email when new articles are posted on . Patients with PBC and cirrhosis treated with seladelpar exhibited greater reductions in ALP, GGT and ALT at 12 ...

Please provide your email address to receive an email when new articles are posted on . In this video, Nancy S. Reau, MD, FAASLD, AGAF, discusses 36-month results from the ongoing phase 3 ASSURE ...

A global study reveals that cutting-edge cancer immunotherapies, while lifesaving, carry a hidden risk: they may trigger cholestasis, a serious liver condition where bile flow stalls. Analyzing 634 ...

ProQR Therapeutics announces a Phase 1 trial of AX-0810 to evaluate safety and target engagement in cholestatic liver disease. The initiation of the Phase 1 clinical trial for AX-0810 is contingent ...

Kayfanda® (odevixibat) approved as new treatment choice for cholestatic pruritus in children from six months with the rare liver condition, Alagille Syndrome E.U. marketing authorization for Kayfanda ...

Bile acids are essential molecules the liver produces that play a critical role in digestion. They help us absorb fat-soluble vitamins and cholesterol from our food. However, bile acids can become a ...

The timing of your final meal might matter more than its content when it comes to liver health. While nutrition science typically focuses on what we eat, emerging research highlights when we eat as ...