Acute hepatic porphyria, or AHP, is a group of rare genetic conditions that affect how the body makes a natural substance called heme. Heme is produced in the liver and is essential for many important ...

What is the appropriate treatment for a patient with acute intermittent porphyria and hepatitis B (e-antigen negative) with a normal alanine transaminase and a hepatitis B virus viral load of 45,000 ...

Please provide your email address to receive an email when new articles are posted on . Clinicians are hoping an RNA interference therapeutic targeting aminolevulinic acid synthase 1, known as ...

Use of the RNA inhibitor givosiran was shown to reduce expression of delta-aminolevulinic acid synthase 1, in turn reducing the severity of acute attacks and chronic symptoms for patients with severe ...

An acute AIP attack may have numerous clinical manifestations. Abdominal pain is not only the most common symptom, but also is often the first sign of an acute attack. [3] Other common symptoms ...

Patients with symptomatic acute hepatic porphyria were found to be at greater risk of accessing long-term sick leave and disability pension compared with the general population, but were not shown to ...

Acute porphyria is a group of uncommon diseases that can cause severe, potentially life-threatening attacks of abdominal pain, nausea, vomiting and paralysis. Liver transplantation is currently the ...

Rights acquired from the University of Navarra, Spain. Amsterdam Molecular Therapeutics (AMT) obtained exclusive, worldwide rights to develop and commercialize AMT-020 as a therapeutic product from ...

Please provide your email address to receive an email when new articles are posted on . In her session, Dickey, an assistant professor at Massachusetts General Hospital, looked at a form of porphyria ...